Both the English and the French versions of the #1 Biology, Evolution, and Genetic Science bestseller Probability Zero are now available in hardcover.
Probabilité zéro: l’Impossibilité mathématique de l’évolution par sélection naturelle has also been translated and published in French by Editions Alpines.
Both hardcovers are also available from NDM Express. We’re placing the initial print order tomorrow, so if you want one direct, order it today and figure about 2-3 weeks for it to get to you. Amazon hasn’t placed their stocking order yet, so it’s probably going to be a similar delivery timeframe.
A German translation is nearly complete and will be available for order before the end of the month.
In other PZ-related news, the complete paper, to which I referred yesterday in the post about Dawkins and the fish of Lake Victoria, is now available for review. It is a multi-taxa test of MITTENS across the tree of life which convincingly demonstrates that the throughput problem is systematic and is not limited to any one divergence between species.
The Universal Failure of Fixation: MITTENS Applied Across the Tree of Life
The MITTENS framework (Mathematical Impossibility of The Theory of Evolution by Natural Selection) previously demonstrated a 220,000-fold shortfall between required and achievable fixations for human-chimpanzee divergence. A reasonable objection holds that this represents an anomaly—perhaps something about the human lineage uniquely violates the model’s assumptions. We test this objection by applying MITTENS systematically across the tree of life: great apes, rodents, birds, fish, equids, elephants, and insects. Across 18 species pairs spanning generation times from two weeks (Drosophila) to 22 years (elephants) and divergence depths from 12,000 years (sticklebacks) to 100 million years (bacteria), we find that every sexually reproducing lineage fails by 2–5 orders of magnitude. The sole exception is
Escherichia coli, which passes due to asexual reproduction (eliminating recombination delay), complete generational turnover (d = 1.0), and astronomical generation counts (~1.75 trillion over 100 MY). Rapid radiations thought to exemplify evolutionary potential—Lake Victoria cichlids (500+ species in 15,000 years), post-glacial sticklebacks—show among the largest shortfalls: 141,000× and 216,000× respectively. Short generation times, which should favor the standard model by providing more opportunities for fixation, do not rescue it. The pattern is systematic and universal. The substitution-fixation model fails not for one troublesome comparison, but for every sexually reproducing lineage examined. The mechanism does not work.





