Covid Round 2

The importance of remembering predictions about the future, however outlandish or insane they might appear, is that the more accurate the predictive model, the more easily one will recognize the developing scenario playing out according to the model. Which is why this published study concerning repeated vaccination creating immune tolerance by the Covid spike protein, is superficially concerning in light of a conspiracy post that has been making the rounds.

Less than a year after the global emergence of the coronavirus SARS-CoV-2, a novel vaccine platform based on mRNA technology was introduced to the market. Globally, around 13.38 billion COVID-19 vaccine doses of diverse platforms have been administered. To date, 72.3% of the total population has been injected at least once with a COVID-19 vaccine. As the immunity provided by these vaccines rapidly wanes, their ability to prevent hospitalization and severe disease in individuals with comorbidities has recently been questioned, and increasing evidence has shown that, as with many other vaccines, they do not produce sterilizing immunity, allowing people to suffer frequent re-infections. Additionally, recent investigations have found abnormally high levels of IgG4 in people who were administered two or more injections of the mRNA vaccines. HIV, Malaria, and Pertussis vaccines have also been reported to induce higher-than-normal IgG4 synthesis. Overall, there are three critical factors determining the class switch to IgG4 antibodies: excessive antigen concentration, repeated vaccination, and the type of vaccine used. It has been suggested that an increase in IgG4 levels could have a protecting role by preventing immune over-activation, similar to that occurring during successful allergen-specific immunotherapy by inhibiting IgE-induced effects. However, emerging evidence suggests that the reported increase in IgG4 levels detected after repeated vaccination with the mRNA vaccines may not be a protective mechanism; rather, it constitutes an immune tolerance mechanism to the spike protein that could promote unopposed SARS-CoV2 infection and replication by suppressing natural antiviral responses. Increased IgG4 synthesis due to repeated mRNA vaccination with high antigen concentrations may also cause autoimmune diseases, and promote cancer growth and autoimmune myocarditis in susceptible individuals.

IgG4 Antibodies Induced by Repeated Vaccination May Generate Immune Tolerance to the SARS-CoV-2 Spike Protein, 17 May 2023

This evidence tends to support the hypothesis of an earlier article published in Forbes that suggested increased IgG4 synthesis might not be effective in telling the immune system to kill cells infected with the virus, and also observed that the percentage of ineffective antibodies was rising over time in vaccinated individuals.

IgG1, IgG2, and IgG3 provide protection not only by blocking the virus from entering cells but also by their Fc regions activating effector functions and signaling the immune system to kill infected cells. IgG4, however, does not activate the effector functions, meaning their presence may impact how the body responds to Covid-19.

To measure the relative frequency of IgG subclasses in the sera of vaccine recipients, Irrgang et al. followed a cohort of 29 healthcare workers, analyzing their sera ten days after a first, second, and third dose, as well as 210 days after the second, and 180 days after the third.

In line with initial efficacy reports for the vaccine, antibody levels were robust throughout the cohort post-first and second doses. The researchers also found that 210 days after the second dose, antibody levels had fallen significantly, reaffirming the loss of antibody protection over time. Again, following the third dose, antibodies rose significantly, only to fall 180 days after the booster.

The most interesting data regards the growing concentration of IgG4 in the cohort’s sera. On average, only 0.04% of the antibody response post-second vaccination was IgG4. 210 days after the second dose, that percentage rose to 4.82%. Following the third dose, IgG4 comprised 13.91%, rising to 19.27% 180 days after.

Emergence Of IgG4 In Long-Term Vaccines: Winning Or Losing The Race?, FORBES, 13 January 2023

Now, I will caution the reader that the following scenario is almost certainly fake, because a) it was posted on Reddit by someone in June 2023, well AFTER the two articles about IgG4 antibodies were published and b) it was posted on Reddit, therefore it only looks dangerously predictive because most people don’t know when it first appeared. While /pol/ may always be right, the converse is true for Reddit. The fact that it has been promulgated without the header showing the date on it strongly suggests that it is nothing more than science horror fiction extrapolated from the two previous articles, so you can consider this a skeptical pre-debunking of sorts.

  • The vax is a de-population tool.
  • The mrna vax has always been about programmable humans. Getting needles in arms to re-write human biology.
  • After booster 4 something called igg4 is permanently active. I am no scientist but can remember igg4 cause my dogs name is iggy. He says it’s like allergy shots but for the covid spike. It tells your body there is nothing wrong with the covid spike and to leave it alone. He says if you look into it, you will see this is already known.
  • The stage is now set, he says over 3 billion people now have adequate levels of igg4 and the final phase is close. He said those in the know call it “the process”. It is to reduce the human population by 5 billion (3 billion from igg4 programming and 2 billion from the fall out of 3 billion deaths).
  • He said late 2023 the new and final covid strain will be released. This strain will have over 90% fatality but only to those who have igg4 in their bodies. They will mount NO immune response to this deadly strain. Unvaxed like him will basically have a mild cold.
  • He said ‘the process’ will do a full psychological warfare media blitz, claiming the vax has caused igg4 and anyone vaxed has a 90% chance of dying from this strain. They will claim all governments knew and misled their people. It will be designed to cause mass panic and turn all citizens against their governments. This will ensure cities burn during the viral outbreak and emergency services are nonexistent. Billions will die.

Nota Rhetorica: that preemptive defense of why the poster remembered the name of the antibody in the third point is also an indicator of a fake, as well as the mindset and IQ of those targeted by the fake.

Only if evidence surfaces proving that the same sort of information preceding the January and May articles should it be taken at face value. Until then, or until the 4x vaxxed begin succumbing like periodical cicadas this autumn, what we actually know is that a new round of flu season is coming, which means a new round of “Covid” is on the way, and it will be followed by the tried-and-tested scare tactics pushing lockdowns and vaccinations, which should be much easier for both purebloods and the vaxxed to resist this second time around.